Below are two photos of the Scythe Setsugen mounted on my Asus 5770 and laid out on a seamstress cutting mat for measurement purposes. It appears as though there is roughly 2.5" from the center of the GPU to the rear/ IO side of the cooler.
The angles/perspectives of the shots don't quite line up with how it measures out.
I selected the Asus CuCore card for it's no reference design to allow room for larger air coolers. I don't have a reference 5770 on hand to take measurements from but it seems to me that if you have more than 2.5" from the center of the GPU to the furthest rearward extreme of your card, you should be good for mounting it.
The back plate for this cooler is a joke - it has a single rubber standoff in the center that really negates the use of it as a structural backplate. Because it stood so far off the back of the card I know for certian you wouldn't be able to use two of these in an "every other" PCIe XFire config. I had to do a jury rigged mounting of the cooler using some of the components of the Asus cooler because there wasn't enough clearance between my CPU cooler and the first PCIe slot.
As mentioned elsewhere, the fan on this cooler comes mounted pointing the wrong direction. I was able to flip it over and it workd fine like this for a few days until the fan started contacting the cooler. I shimmed the corners of the fan up about 2mm to take up the necessary space.
Idle temps are 34C with the fan at 20% and load (Furmark, 5 minutes) at 57C with the fan at 50%[/img]