Be sure to:
- make an image/backup of your HDD. Then test it out to make sure it works

- update your BIOS before the swap so your mobo recognizes the CPU
- reset CMOS prior to starting up.
- adjust the bios settings to make sure the north bridge, memory bus, etc is set for speeds that will run without problems....
- boot windows into safe mode so none of your startup programs (like antivirus programs etc) run during bring up mode.
- use memtest and prime95 to make sure the system is stable.
Otherwise, your system could boot up into a default speed that causes memory corruption...then watch as your A/V program starts up and looks over your hard drive...corrupting data as it scans. (my personal horror story)